„Knowledge becomes health“ – we are filling this motto with life every day, developing new ideas and improv-ing old-established knowledge. The University Hospital Frankfurt has existed since 1914. Our around 7,500 employees contribute with their skills and knowledge to the 32 specialist clinics, theoretical clinical institutes, and administrative departments. The close connection of health care with research and teaching, as well as a climate of collegiality, internationality, and cross-professional cooperation characterize the university hospital.

PhD Students – Quantitative Spatial Cancer Biology Research Group

(We are targeting applicants of all genders)
Full time | limited | Announcement number: 976-2022

We are seeking two motivated PhD Students to join our »Quantitative Spatial Cancer Biology“ research group at the Dr. Senckenberg Institute of Pathology and the Mildred Scheel Career Center (MSNZ) Frankfurt , an excellence program supporting careers in translational cancer research (funded by the German Cancer Aid). The lab, headed by Dr. Konstantinos Kokkaliaris, specializes in hematopoietic stem-cell biology and bone marrow tissue organization in health and cancer. We use innovate single-cell protein profiling technologies including cutting-edge multiplexed tissue imaging, multicolor flow cytometry and mass cytometry. The focus of the lab is to profile complex 3D tissue organization, uncover functional cell-cell interactions in homeostasis, cancer and aging and further develop multiplex tissue imaging modalities.

Project Description

The projects aim at defining the key cellular, molecular and structural alterations in bone marrow tissue in hematologic diseases and bone metastasis. We will focus on targetable interactions between disease-initiating cells, healthy hematopoietic stem cells and their tissue microenvironment(s). Our goal is to leverage those findings towards the design of novel therapeutic intervention strategies to prolong disease-free survival while supporting healthy tissue function.

We expect

Master’s degree in life sciences, biology or equivalent
Passion for discovery, collaborative spirit & good communication skills
Basic experience in laboratory techniques (i.e. molecular biology)
Good knowledge of English
Previous experience on the biology of hematologic diseases or metastasis is a strong plus
Due to legal regulation an employment relationship may only be entered by people who are vaccinated against or have recovered from COVID-19. A valid proof of measles immunity / measles vaccination is also required.

What we offer

Collective agreement : In addition to an attractive salary based on a collective agreement (65% E13) with an annual special payment, you benefit from long-term security through company pension schemes

Mobility : Free public transport in all Hessen (Free State Ticket Hessen)

Campus : Our attractive university hospital campus offers a modern cafeteria, various cafes, and opportunities to rest in numerous green spaces. A walk on the riverside of the Main offers relaxation during breaks

Work-Life-Balance : We offer childcare in our daycare center (more information can be found here ), child care during holidays, and many attractive offers for health promotion

Professional development : Internal and external training for your professional development

Women are underrepresented in these positions at the University Hospital Frankfurt. Applications from women are therefore particularly welcome. Disabled applicants are preferred if they have the same personal and professional qualifications.

Join our team

Use the time until December 25, 2022 to apply. Please state the announcement number, a possible starting time and submit your application including your CV, short motivation statement (1-2 paragraphs) and one reference letter. For further information on the position, please contact Dr. Konstantinos Kokkaliaris (email: konstantinos.kokkaliaris@kgu.de ; Twitter: @kd_kokkaliaris).

Apply now
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